Due to its anti-inflammatory role, CBD is a very promising therapeutic agent for a variety of inflammatory and pain-associated disorders.
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Other Anti-inflammatory Mechanisms:
CBD also reduced anxiety caused by the use of THC [R].
Researchers suggest that it may be effective for panic disorder, obsessive-compulsive disorder and post-traumatic stress disorder [R].
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CBD significantly decreased chronic inflammatory and neuropathic pain in rodents [R].
Cannabidiol, especially in a combination with THC, shows promising results for the treatment of postoperative pain, chronic pain associated with multiple sclerosis, cancer, rheumatoid arthritis, and neuropathic pain [R, R, R].
Studies show that CBD and opioids act together to relieve pain [R].
Due to its anti-inflammatory effect, cannabinoids may provide relief of joint pain and swelling, and decrease joint destruction and disease progression [R].
Administration of CBD protected joints against severe damage, decreased progression, and produced improvement of arthritis in animal models [R].
The first controlled trial showed that administration of Sativex over 5 weeks produced significant improvements in the intensity of pain on movement and at rest, quality of sleep, and inflammation. No serious adverse effects were observed [R].
A study showed that CBD relieved nausea and vomiting when it was given to rats [R].
THC is an approved drug used to treat nausea and vomiting (dronabinol) in human patients, but more clinical studies proving the efficacy of CBD are needed in humans [R].
According to the National Cancer Institute, CBD increases appetite by binding to cannabinoid receptors in the body [R].
CBD oil helped me greatly reduce my food sensitivities. If you struggle with food sensitivities, I’d recommend experimenting with CBD oil as well as the Lectin Avoidance Diet, a diet specifically designed to help you pinpoint the exact foods that give you a reaction so you can start eating worry free.
A study, which included 4,657 adult men and women, showed that current marijuana use was associated with 16% lower fasting insulin levels, and smaller waist circumferences, a factor connected to the onset of diabetes [R].
Cannabidiol can inhibit and delay the destruction of insulin-producing pancreatic cells and the production of inflammatory cytokines in diabetics [R].
This data strengthens assumptions that CBD, which is known to be safe in humans, can possibly be used as a therapeutic agent for treatment of type 1 diabetes at an early stage of the disease [R].
A study reported that CBD caused dilation of arteries and protected blood vessel from damage in animal models [R].
However, further work is required to prove the ability of CBD to prevent the development of heart and blood vessels disorders in humans.
The combination of CBD and THC may reduce inflammation and relieve symptoms of IBD, such as abdominal pain, diarrhea, and reduced appetite [R].
CBD showed some antimicrobial activity against methicillin-resistantStaphylococcus Aureus (MRSA), a bacterium that causes difficult-to-treat infections [R].
Studies show cannabidiol inhibits prions, the proteins that cause fatal neurodegenerative diseases like Creutzfeldt-Jakob disease and mad cow disease, increasing the survival time of infected mice by almost a week [R].
Rodents with broken limbs healed much faster when treated with CBD [R].
CBD Reduces Dyskinesia
Dyskinesia causes involuntary movements.
CBD (combined with a TRPV-1 blocker) reduced the symptoms of dyskinesia in mice [R].
Research suggests taking CBD before bed improves sleep in people with insomnia [R].
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Studies suggest that CBD may be therapeutic for substance use disorders.
Research suggests that inhaling cannabidiol for a week might reduce the number of cigarettes smoked by about 40%, without increasing cravings for nicotine.
CBD decreases lipid synthesis and proliferation of human sebaceous glands, and has an anti-inflammatory effect on sebaceous glands, thus having a potential as atherapeutic agent for the treatment of acne vulgaris [R].
CBD reduces the growth of skin cells (keratinocytes), playing a potential role in the treatment of psoriasis [R].
When CBD is combined with THC, it causes a temporary lack of drive. There is an impairment of reward learning and motivation [R].
Hemp nuts sold for dietary consumption are within acceptable standards for the quantity of CBD and THC [R].
CBD is well tolerated, and safe at high doses, and with chronic use in humans [R].